Weiss-Kruszka syndrome is a rare neurodevelopmental disorder characterized by craniofacial anomalies, developmental delay, and autistic features. Researchers at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences and the Keck School of Medicine of the University of Southern California (USC) in Los Angeles uncovered the molecular mechanism underlying Weiss-Kruszka syndrome: The causative Read More…
Author: lytal
Drug-like molecule points to novel strategies for cancer therapy
A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes. In a new study in Cell Chemical Biology, a team of scientists led by Oliver Bell from USC and Stephen V. Frye from Read More…
Paper Published in Science Advances
Design redundancy is not only an invention of engineers for building machines, but also a principle of nature for designing organisms. This principle is at play in the regulation of the genes responsible for directing stem cells to multiply themselves in the developing mouse embryo, as described in a new study in Science Advances. In Read More…
Paper Published in Cell Chemical Biology
“Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7,” by Lamb et. al. was published in Cell Chemical Biology on August 15, 2019.
Paper Featured in Nature Communications Editors’ Highlights
The lab’s paper “Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing,” (Moussa & Bsteh et al. 2019) has been featured in Nature Communications’ Editors’ Highlights, under Carolina Perdigoto’s Genomes and Epigenomes focus.
Paper Published in Nature Communications
“Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing,” by Moussa & Bsteh et al., was published in Nature Communications on April 29, 2019.
